By Eric Schmidt

The Buffalo Bills appear to be headed into the final weeks of the NFL without running back Fred Jackson. In the fourth quarter against the St. Louis Rams on Sunday, Jackson suffered a knee injury, after receiving a blow to his knee from a helmet. His injury was originally believed to be very severe, but head coach Chan Gailey has told reporters that he will likely miss 2-3 weeks, almost certainly ending his 2012 season.

Jackson struggled this season, finishing the season with just 437 yards on 115 carries, for a career low 3.8 yards per carry. Jackson also found the endzone just three times. Watch his role with the Buffalo Bills diminish next season with the emergence of C.J. Spiller this season.

Fantasy implications- Spiller will once again become the lead back for the Bills going forward. He has posted a very impressive 6.6 yards per carry for 944 yards on 144 carries with 6 total scores. Many fantasy playoff have already begun or will be starting next week. Spiller had just 37 yards on eight carries against the Rams on Sunday. Next up, the Seattle Seahawks for the Bills game in Toronto. The Seahawks are a very formidable team on defense so the expectations for Spiller should be tempered this week.

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